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- Module 2 Overview
Evaluation, Staging, and Monitoring of Chronic Hepatitis C - 0%Lesson 1
Initial Evaluation of Persons with Chronic HCVActivities- 0%Lesson 2
Natural History of HCV InfectionActivities- 0%Lesson 3
Counseling Persons with Chronic HCV InfectionActivities- 0%Lesson 4
Evaluation and Staging of Liver FibrosisActivities- 0%Lesson 5
Evaluation and Prognosis of Persons with CirrhosisEvaluation, Staging, and Monitoring of Chronic Hepatitis C Overview3rd Edition
Module Core Competency
Provide Evidence-Based Evaluation, Staging, and Monitoring to Persons with Chronic Hepatitis C Infection
Target Audience
Intended for clinicians involved in long-term management of persons with chronic hepatitis C infection. Content includes initial evaluation, natural history, preventing liver damage, staging of liver fibrosis, evaluation of cirrhosis, surveillance for hepatocellular carcinoma, and recognition of extrahepatic manifestations.Editor
H. Nina Kim, MD, MScH. Nina Kim, MD, MSc
Professor of Medicine
Division of Allergy & Infectious Diseases
University of WashingtonDisclosures: Grant to institution: Gilead SciencesFree CNE/CME
Module Lessons
1Lesson 1 Initial Evaluation of Persons with Chronic HCV
- Learning Objectives
- Describe key aspects of the medical history to obtain in a new evaluation of persons with HCV infection
- Identify key abnormal physical examination findings that may be present in a person with HCV and cirrhosis
- Summarize recommended laboratory studies to obtain for a person with HCV at the initial evaluation visit
- List immunizations that should be administered to persons with chronic HCV infection
- Discuss the evaluation of secondary causes of liver disease in persons with chronic HCV infection
- Quick ReferenceInitial Evaluation of Persons with Chronic HCV Core Concepts
- Activity 1B.Calculating Body Mass Index (BMI)
- Activity 1C.Determining AUDIT-C Score
2Lesson 2 Natural History of HCV Infection
- Learning Objectives
- Summarize spontaneous viral clearance versus persistent infection following initial HCV acquisition
- Describe the variable outcomes that can occur in persons with chronic HCV infection
- List factors that influence the rate of progression of fibrosis in persons with chronic HCV infection
- Discuss the impact of alcohol intake on fibrosis progression in persons with chronic HCV infection
- Quick ReferenceNatural History of HCV Infection Core Concepts
3Lesson 3 Counseling Persons with Chronic HCV Infection
- Learning Objectives
- Determine which common liver health counseling messages should be addressed in persons with chronic HCV infection
- Explain recommendations for intake of acetaminophen and nonsteroidal antiinflammatory medications in persons with chronic HCV infection
- Discuss key counseling messages related to coffee, diet, and complementary medications in persons with chronic HCV infection
- Clarify guidance related to alcohol and marijuana use in persons with chronic HCV infection
- Quick ReferenceCounseling Persons with Chronic HCV Infection Core Concepts
4Lesson 4 Evaluation and Staging of Liver Fibrosis
- Learning Objectives
- Explain the indications, risks, and histologic assessment for liver biopsy in persons with chronic HCV infection
- Discuss noninvasive Indirect and direct tests of liver fibrosis and examine the potential clinical utility of these tests
- Summarize key radiologic methods that can estimate hepatic fibrosis
- Quick ReferenceEvaluation and Staging of Liver Fibrosis Core Concepts
- Activity 4B.Calculating APRI
5Lesson 5 Evaluation and Prognosis of Persons with Cirrhosis
- Learning Objectives
- Differentiate compensated cirrhosis from decompensated cirrhosis
- Explain the classification and prognostic systems for cirrhosis
- Summarize important aspects of the medical history and physical examination in persons with cirrhosis
- Describe key manifestations and complications associated with decompensated cirrhosis
- Quick ReferenceEvaluation and Prognosis of Persons with Cirrhosis Core Concepts
6Lesson 6 Surveillance for Hepatocellular Carcinoma
- Learning Objectives
- Discuss the incidence of hepatocellular carcinoma in persons with chronic HCV
- Describe the rationale for hepatocellular carcinoma surveillance in persons with chronic HCV infection
- Compare different surveillance testing methods used for hepatocellular carcinoma surveillance
- Summarize the American Association for the Study of Liver Diseases (AASLD) recommendations for surveillance for hepatocellular carcinoma
- Quick ReferenceSurveillance for Hepatocellular Carcinoma Core Concepts
7Lesson 7 Extrahepatic Conditions Related to HCV infection
- Learning Objectives
- Identify the most common clinical syndromes associated with HCV-related cryoglobulinemia
- Describe the renal extrahepatic manifestations associated with chronic HCV infection
- Recognize the most common dermatologic extrahepatic manifestations associated with chronic HCV infection
- Explain the relationship of chronic HCV infection and lymphomas
- Quick ReferenceExtrahepatic Conditions Related to HCV infection Core Concepts
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- 0%Lesson 2
Funded by
Centers for Disease Control and Prevention Cooperative Agreement (CDC-RFA-PS21-2105)
Created at
University of Washington
Part of
IDEA Platform
CME provided byUniversity of Alabama Birmingham
CNE provided byUniversity of Washington School of Nursing
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