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- Module 6 Overview
Treatment of Key Populations and Unique Situations - 0%Lesson 1
Treatment of Acute HCV InfectionActivities- 0%Lesson 2
Treatment of HCV in Persons with HIV CoinfectionActivities- 0%Lesson 3
Treatment of HCV in Persons with Renal ImpairmentActivities- 0%Lesson 4
Treatment of HCV in Persons with CirrhosisActivities- 0%Lesson 5
Treatment of HCV in Persons with Substance UseActivities- 0%Lesson 6
Treatment of HCV in a Correctional SettingActivities- 0%Lesson 7
Management of Health Care Personnel Exposed to HCVActivities- 0%Lesson 8
Perinatal HCV TransmissionActivitiesTreatment of Key Populations and Unique Situations Overview3rd Edition
Module Core Competency
Apply Evidence-Based HCV Treatment to Key Populations and in Unique Situations
Target Audience
Designed for clinicians who manage key populations of persons living with HCV and/or complex HCV-related unique treatment issues. Material covered is at an advanced level.Editor
David H. Spach, MDDavid H. Spach, MD
Professor of Medicine
Division of Allergy & Infectious Diseases
University of WashingtonDisclosures: NoneFree CE CNE/CME
Module Lessons
1Lesson 1 Treatment of Acute HCV Infection
- Learning Objectives
- Explain the concept of spontaneous HCV clearance after acute infection and how this impacts treatment strategies
- Formulate an approach to evaluation and treatment of persons with acute HCV infection
- Summarize treatment recommendations for persons diagnosed with acute HCV infection
- Quick ReferenceTreatment of Acute HCV Infection Core Concepts
- Activity 1B.Increases in HCV Infection in Young Persons in United States
2Lesson 2 Treatment of HCV in Persons with HIV Coinfection
- Learning Objectives
- Explain the impact of HIV on coinfection with HCV
- Discuss sustained virologic response (SVR) outcomes demonstrated in key studies using direct-acting antiviral agents to treat HCV in persons with HIV coinfection
- Differentiate HCV treatment duration for HCV monoinfection versus HCV-HIV coinfection
- Summarize recommendations for monitoring persons with HCV-HIV coinfection after initiating antiretroviral therapy
- Highlight drug interactions from the perspective of direct-acting antivirals and antiretroviral medication classes
- Quick ReferenceTreatment of HCV in Persons with HIV Coinfection Core Concepts
- Activity 2B.DHHS Guidelines for HCV-HIV Coinfection
3Lesson 3 Treatment of HCV in Persons with Renal Impairment
- Learning Objectives
- Explain the interaction of HCV and renal disease
- Discuss HCV treatment approaches in persons with chronic renal insufficiency
- Summarize HCV treatment recommendations in persons following renal transplantation
- Quick ReferenceTreatment of HCV in Persons with Renal Impairment Core Concepts
- Activity 3B.GFR Calculator
4Lesson 4 Treatment of HCV in Persons with Cirrhosis
- Learning Objectives
- Distinguish persons with compensated cirrhosis from those with decompensated cirrhosis
- Summarize the impact of treating HCV in persons with cirrhosis
- Provide appropriate HCV treatment options for persons with compensated cirrhosis
- Discuss approaches to treatment of HCV in persons with decompensated cirrhosis
- Quick ReferenceTreatment of HCV in Persons with Cirrhosis Core Concepts
- Activity 4B.Understanding Liver Biopsy Results
5Lesson 5 Treatment of HCV in Persons with Substance Use
- Learning Objectives
- Summarize the impact of substance use on HCV treatment decisions
- Describe HCV treatment responses in persons with substance use disorders compared with those who do not have substance use disorders
- Integrate support services and management strategies into programs for persons with substance use disorders who have chronic HCV infection
- Quick ReferenceTreatment of HCV in Persons with Substance Use Core Concepts
6Lesson 6 Treatment of HCV in a Correctional Setting
- Learning Objectives
- Describe HCV prevalence in the correctional setting
- Summarize HCV screening in correctional setting
- Discuss challenges of treating HCV in corrections
- Quick ReferenceTreatment of HCV in a Correctional Setting Core Concepts
- Activity 6B.Hepatitis C in Corrections
7Lesson 7 Management of Health Care Personnel Exposed to HCV
- Learning Objectives
- List the definition for health care personnel
- Estimate the risk of HCV seroconversion after an occupational exposure to HCV
- Describe management of health care personnel exposed to HCV, based on type and nature of exposure
- Discuss monitoring and follow-up testing of health care personnel after an occupational exposure to HCV
- Quick ReferenceManagement of Health Care Personnel Exposed to HCV Core Concepts
8Lesson 8 Perinatal HCV Transmission
- Learning Objectives
- Describe the current guidelines for HCV screening in pregnant women
- Identify the risk of mother-to-child transmission of HCV and factors associated with increased risk of transmission
- Summarize the impact of HCV on pregnancy outcomes
- Describe interventions or prophylactic measures to reduce the risk of mother-to-child transmission of HCV
- Quick ReferencePerinatal HCV Transmission Core Concepts
- Background
- HCV Screening During Pregnancy
- Factors Associated with HCV Perinatal Transmission
- Impact of Chronic HCV Infection on Pregnancy
- Effect of Pregnancy on Chronic HCV
- Interventions to Prevent Mother-to-Child Transmission of HCV
- Safety of HCV Treatment During Pregnancy and Breastfeeding
- Monitoring of Pregnant Women with HCV
- Management of Neonates Born to Mothers with HCV Infection
- Summary Points
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