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Treatment of HCV

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Core Competencies

Simplified HCV Treatment for All HCV Genotypes

Topic
Learning Objectives
Introduction
Eligibility for Simplified HCV Treatment: Initial Assessment
Simplified Treatment: Pretreatment Assessment for Patients without Cirrhosis
Recommended Simplified Treatment Regimens for Patients without Cirrhosis
Monitoring on and after HCV Treatment in Patients without Cirrhosis
Simplified Treatment: Pretreatment Assessment for Patients with Compensated Cirrhosis
Recommended Simplified Treatment Regimens for Patients with Compensated Cirrhosis
Monitoring On and After Treatment for Patients with Compensated Cirrhosis
Treatment Interruptions
Summary Points

Retreatment of Patients with Prior HCV Treatment Experience

Topic
Learning Objectives
Introduction
Special Considerations with Retreatment
Treatment Failure with Sofosbuvir-Containing DAA or Elbasvir-Grazoprevir
Treatment Failure with Glecaprevir-Pibrentasvir
Treatment Failure with Multiple DAA Regimens
Summary Points

Monitoring During and After HCV Treatment

Topic
Learning Objectives
Background
Monitoring for Treatment Efficacy
Monitoring for Safety at Baseline and During Treatment
Hepatitis B Reactivation Associated with HCV DAA Therapy
Monitoring After Receiving HCV Therapy
Summary Points

Treatment of HCV in Persons with Cirrhosis

Topic
Learning Objectives
Background
Impact of Treating HCV in Persons with Cirrhosis
Treating HCV in Persons with Compensated Cirrhosis
Treating HCV in Persons with Decompensated Cirrhosis
Summary Points

Treatment of Acute HCV Infection

Topic
Learning Objectives
Background
Spontaneous Clearance of HCV Following Acute Infection
Comprehensive Clinical Care during Workup for Acute HCV
Acute HCV Treatment Data
AASLD-IDSA Guidance for Management of Acute HCV
Summary Points

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