Section Navigation
Section Navigation
- Module 8 Overview
HCV Test and Cure - 0%Lesson 1
Epidemiology and Natural HistoryActivities- 0%Lesson 2
Screening, Diagnosis, and PreventionActivities- 2A.Core Concepts
- 2B.Interpretation of HCV Diagnostic Laboratory Test Results
- 2C.Strategies for Implementing Hepatitis C Virus Point-of-Care Testing
- 0%Lesson 3
Pretreatment Evaluation and Fibrosis StagingActivities- 3A.Core Concepts
- 3B.FibroScan: A Clinician's Guide
- 3C.Calculating FIB-4 Score
- 3D.Calculating a CTP Score
- 0%Lesson 4
HCV Simplified TreatmentActivities- 4A.Core Concepts
- 4B.HCV Point of Care Testing and the Test and Treat Approach
- 4C.Simplified Treatment Criteria
- 4D.Recommended Regimens for Simplified Treatment Approach
- 4E.Follow up After the HCV Test and Treat Approach
- 4F.Initiation of HCV Treatment in Person with Alcohol Use Disorder
- 4G.Glecaprevir-Pibrentasvir Treatment with Compensated Cirrhosis
- 4H.Sofosbuvir-Velapatasvir Treatment with Compensated Cirrhosis
- 4I.Drug Interactions with Glecaprevir-Pibrentasvir
- 4J.Drug Interactions with Sofosbuvir-Velpatasvir
- 4K.Management of Treatment Interruption with less than 7 Missed Days
- 4L.Management of Treatment Interruption After Missing 8-20 Days
- 0%Lesson 5
Follow-Up and Promoting Liver HealthQuick
ReferenceHCV Test and Cure Overview4th Edition
Module Core Competency
Target Audience
In this hepatitis C fundamentals 5-hour, highly interactive module, health care providers will develop core proficiency in screening and diagnosing hepatitis C, providing simplified treatment of hepatitis C with direct acting antivirals (DAAs), and assessing for cure. Learners who complete all five lessons in this module may take an optional 20-question knowledge assessment test and earn an HCV Test and Cure Training Certificate.1Lesson 1 Epidemiology and Natural History
- Learning Objectives
- Increase treatment rates in the United States for adults with hepatitis C virus (HCV) infection
- Describe key epidemiologic features of HCV infection in the United States
- Utilize knowledge about HCV acquisition to prevent new HCV infections
- Recognize the progression of liver disease in untreated HCV infection
- Adopt the simplified HCV treatment approach to expand treatment of HCV by primary care clinicians
- Quick ReferenceEpidemiology and Natural History Core Concepts
- Activity 1B.Welcome Video
2Lesson 2 Screening, Diagnosis, and Prevention
- Learning Objectives
- Perform universal HCV screening in persons in the United States
- Recognize HCV acquisition factors to inform periodic, repeat HCV testing
- Effectively implement HCV testing sequence recommendations from the Centers for Disease Control and Prevention
- Correctly interpret HCV antibody and HCV RNA test results to determine HCV status
- Counsel persons with HCV on how to prevent HCV transmission
- Quick ReferenceScreening, Diagnosis, and Prevention Core Concepts
- Activity 2B.Interpretation of HCV Diagnostic Laboratory Test Results
- Activity 2C.Strategies for Implementing Hepatitis C Virus Point-of-Care Testing
3Lesson 3 Pretreatment Evaluation and Fibrosis Staging
- Learning Objectives
- Initiate a comprehensive clinical and laboratory evaluation prior to treating a person for HCV infection
- Obtain the recommended core set of laboratory tests indicated for persons prior to starting HCV treatment
- Differentiate laboratory testing recommendations in persons with HCV based on cirrhosis status
- Correctly interpret test results for noninvasive assessment tools used to stage liver fibrosis
- Recognize the conditions that would lead to a presumptive diagnosis of decompensated cirrhosis
- Quick ReferencePretreatment Evaluation and Fibrosis Staging Core Concepts
- Activity 3B.FibroScan: A Clinician's Guide
- Activity 3C.Calculating FIB-4 Score
- Activity 3D.Calculating a CTP Score
4Lesson 4 HCV Simplified Treatment
- Learning Objectives
- Provide a rationale for treating all people with HCV except persons with less than a 12-month life expectancy
- Adhere to inclusion and exclusion criteria for who is eligible to receive simplified HCV treatment
- Choose an appropriate recommended regimen for simplified HCV treatment
- Conduct laboratory monitoring for persons receiving simplified HCV treatment, including assessment for sustained virologic response
- Manage incomplete treatment adherence based on time into treatment and number of days of missed doses
- Quick ReferenceHCV Simplified Treatment Core Concepts
- Activity 4B.HCV Point of Care Testing and the Test and Treat Approach
- Activity 4C.Simplified Treatment Criteria
- Activity 4D.Recommended Regimens for Simplified Treatment Approach
- Activity 4E.Follow up After the HCV Test and Treat Approach
- Activity 4F.Initiation of HCV Treatment in Person with Alcohol Use Disorder
- Activity 4G.Glecaprevir-Pibrentasvir Treatment with Compensated Cirrhosis
- Activity 4H.Sofosbuvir-Velapatasvir Treatment with Compensated Cirrhosis
- Activity 4I.Drug Interactions with Glecaprevir-Pibrentasvir
- Activity 4J.Drug Interactions with Sofosbuvir-Velpatasvir
- Activity 4K.Management of Treatment Interruption with less than 7 Missed Days
- Activity 4L.Management of Treatment Interruption After Missing 8-20 Days
5Lesson 5 Follow-Up and Promoting Liver Health
- Learning Objectives
- Perform follow-up monitoring of persons after treatment for chronic HCV
- Obtain an HCV RNA assay as appropriate to screen for HCV reinfection after a person clears HCV
- Administer priority immunizations for people with chronic HCV
- Engage a person with chronic or cleared HCV in a discussion about measures that promote liver health
- Institute routine screening for hepatocellular carcinoma and varices for persons with cirrhosis
- Quick ReferenceFollow-Up and Promoting Liver Health Core Concepts
- Activity 5B.Determing AUDIT-C Score
- Activity 5C.How to Use Liver Tox
Share by e-mail
Check
-On-
Learning
QuestionsThe Check-on-Learning Questions are short and topic related. They are meant to help you stay on track throughout each lesson and check your understanding of key concepts.You must be signed in to customize your interaction with these questions.
- 0%Lesson 2
Funded by
Centers for Disease Control and Prevention (CDC)
Cooperative Agreement (CDC-RFA-PS21-2105)
Created at
Part of
CME provided by
CNE approved by
Since you've received 80% or better on this quiz, you may claim continuing education credit.
You seem to have a popup blocker enabled. If you want to skip this dialog please Always allow popup windows for the online course.
Current Version: nhcvc-monorepo-339fb90b-2025-05-10-062632
Become a New User
Account Registration Benefits:
- Track your progress on the lessons
- Earn free CNE/CME/CE
- Earn Certificates of Completion
- Access to other free IDEA curricula
Create a free account to get started