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- Module 8 Overview
HCV Test and Cure - 0%Lesson 1
Epidemiology and Natural HistoryActivities- 0%Lesson 2
Screening, Diagnosis, and PreventionActivities- 2A.Core Concepts
- 2B.Interpretation of HCV Diagnostic Laboratory Test Results
- 2C.Strategies for Implementing Hepatitis C Virus Point-of-Care Testing
- 0%Lesson 3
Pretreatment Evaluation and Fibrosis StagingActivities- 3A.Core Concepts
- 3B.FibroScan: A Clinician's Guide
- 3C.Calculating FIB-4 Score
- 3D.Calculating a CTP Score
- 0%Lesson 4
HCV Simplified TreatmentActivities- 4A.Core Concepts
- 4B.HCV Point of Care Testing and the Test and Treat Approach
- 4C.Simplified Treatment Criteria
- 4D.Recommended Regimens for Simplified Treatment Approach
- 4E.Follow up After the HCV Test and Treat Approach
- 4F.Initiation of HCV Treatment in Person with Alcohol Use Disorder
- 4G.Glecaprevir-Pibrentasvir Treatment with Compensated Cirrhosis
- 4H.Sofosbuvir-Velapatasvir Treatment with Compensated Cirrhosis
- 4I.Drug Interactions with Glecaprevir-Pibrentasvir
- 4J.Drug Interactions with Sofosbuvir-Velpatasvir
- 4K.Management of Treatment Interruption with less than 7 Missed Days
- 4L.Management of Treatment Interruption After Missing 8-20 Days
- 0%Lesson 5
Follow-Up and Promoting Liver HealthQuick
ReferenceHCV Test and Cure Overview4th Edition
Module Core Competency
Target Audience
In this hepatitis C fundamentals 5-hour, highly interactive module, health care providers will develop core proficiency in screening and diagnosing hepatitis C, providing simplified treatment of hepatitis C with direct acting antivirals (DAAs), and assessing for cure. Learners who complete all five lessons in this module may take an optional 20-question knowledge assessment test and earn an HCV Test and Cure Training Certificate.1Lesson 1 Epidemiology and Natural History
- Learning Objectives
- Increase treatment rates in the United States for adults with hepatitis C virus (HCV) infection
- Describe key epidemiologic features of HCV infection in the United States
- Utilize knowledge about HCV acquisition to prevent new HCV infections
- Recognize the progression of liver disease in untreated HCV infection
- Adopt the simplified HCV treatment approach to expand treatment of HCV by primary care clinicians
- Quick ReferenceEpidemiology and Natural History Core Concepts
- Activity 1B.Welcome Video
2Lesson 2 Screening, Diagnosis, and Prevention
- Learning Objectives
- Perform universal HCV screening in persons in the United States
- Recognize HCV acquisition factors to inform periodic, repeat HCV testing
- Effectively implement HCV testing sequence recommendations from the Centers for Disease Control and Prevention
- Correctly interpret HCV antibody and HCV RNA test results to determine HCV status
- Counsel persons with HCV on how to prevent HCV transmission
- Quick ReferenceScreening, Diagnosis, and Prevention Core Concepts
- Activity 2B.Interpretation of HCV Diagnostic Laboratory Test Results
- Activity 2C.Strategies for Implementing Hepatitis C Virus Point-of-Care Testing
3Lesson 3 Pretreatment Evaluation and Fibrosis Staging
- Learning Objectives
- Initiate a comprehensive clinical and laboratory evaluation prior to treating a person for HCV infection
- Obtain the recommended core set of laboratory tests indicated for persons prior to starting HCV treatment
- Differentiate laboratory testing recommendations in persons with HCV based on cirrhosis status
- Correctly interpret test results for noninvasive assessment tools used to stage liver fibrosis
- Recognize the conditions that would lead to a presumptive diagnosis of decompensated cirrhosis
- Quick ReferencePretreatment Evaluation and Fibrosis Staging Core Concepts
- Activity 3B.FibroScan: A Clinician's Guide
- Activity 3C.Calculating FIB-4 Score
- Activity 3D.Calculating a CTP Score
4Lesson 4 HCV Simplified Treatment
- Learning Objectives
- Provide a rationale for treating all people with HCV except persons with less than a 12-month life expectancy
- Adhere to inclusion and exclusion criteria for who is eligible to receive simplified HCV treatment
- Choose an appropriate recommended regimen for simplified HCV treatment
- Conduct laboratory monitoring for persons receiving simplified HCV treatment, including assessment for sustained virologic response
- Manage incomplete treatment adherence based on time into treatment and number of days of missed doses
- Quick ReferenceHCV Simplified Treatment Core Concepts
- Activity 4B.HCV Point of Care Testing and the Test and Treat Approach
- Activity 4C.Simplified Treatment Criteria
- Activity 4D.Recommended Regimens for Simplified Treatment Approach
- Activity 4E.Follow up After the HCV Test and Treat Approach
- Activity 4F.Initiation of HCV Treatment in Person with Alcohol Use Disorder
- Activity 4G.Glecaprevir-Pibrentasvir Treatment with Compensated Cirrhosis
- Activity 4H.Sofosbuvir-Velapatasvir Treatment with Compensated Cirrhosis
- Activity 4I.Drug Interactions with Glecaprevir-Pibrentasvir
- Activity 4J.Drug Interactions with Sofosbuvir-Velpatasvir
- Activity 4K.Management of Treatment Interruption with less than 7 Missed Days
- Activity 4L.Management of Treatment Interruption After Missing 8-20 Days
5Lesson 5 Follow-Up and Promoting Liver Health
- Learning Objectives
- Perform follow-up monitoring of persons after treatment for chronic HCV
- Obtain an HCV RNA assay as appropriate to screen for HCV reinfection after a person clears HCV
- Administer priority immunizations for people with chronic HCV
- Engage a person with chronic or cleared HCV in a discussion about measures that promote liver health
- Institute routine screening for hepatocellular carcinoma and varices for persons with cirrhosis
- Quick ReferenceFollow-Up and Promoting Liver Health Core Concepts
- Activity 5B.Determing AUDIT-C Score
- Activity 5C.NIH Liver Tox
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