Grading System Used for AASLD-IDSA Hepatitis C Guidance
| Classification | Description |
|---|---|
| Class I | Conditions for which there is evidence and/or general agreement that a given diagnostic evaluation, procedure, or treatment is beneficial, useful, and effective |
| Class II | Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness and efficacy of a diagnostic evaluation, procedure, or treatment |
| Class IIa | Weight of evidence and/or opinion is in favor of usefulness and efficacy |
| Class IIb | Usefulness and efficacy are less well established by evidence and/or opinion |
| Class III | Conditions for which there is evidence and/or general agreement that a diagnostic evaluation, procedure, or treatment is not useful and effective or if it in some cases may be harmful |
| Level of Evidence | Description |
|---|---|
| Level A | Data derived from multiple randomized clinical trials or meta-analyses |
| Level B | Data derived from a single randomized trial, or nonrandomized studies |
| Level C | Consensus opinion of experts, case studies, or standard of care |



