Activity 5C. How to Use Liver Tox

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Instructions: Read the case history, then use the LiverTox link and read the brief summary on St. John's Wort, with a particular focus on the liver toxicity section.

Background

A 57-year-old woman presents to your clinic for a routine follow-up appointment. She has a history of anxiety, depression, and chronic hepatitis C virus (HCV). She recently started taking St. John’s Wort for her anxiety and depression and has been seeing a therapist. She is getting ready to start on treatment for HCV, and she asks you if St. John’s Wort is safe for her liver.

Open How to Use Liver Tox

Activity Question

You should answer this question after completing the activity.

You must answer all of the questions before checking your work.

This activity has a Check on Learning question. - Show Question

Which one of the following best describes St. John’s Wort in relation to potential hepatoxicity and drug interactions?

There is no evidence that St. John's Wort caused hepatotoxicity or any clinically-relevant drug interactions

There is a high rate of hepatotoxicity directly caused by St. John's Wort

St. John's Wort has effects on P450 enzyme system and may cause significant drug interactions

The Check-on-Learning Questions are short and topic related. They are meant to help you stay on track throughout each lesson and check your understanding of key concepts.

HCV Test and Cure

Screening and Diagnosis of Hepatitis C Infection

Evaluation, Staging, and Monitoring of Chronic Hepatitis C

Management of Cirrhosis-Related Complications

Evaluation and Preparation for Hepatitis C Treatment

Treatment of Hepatitis C Infection

Treatment of Key Populations and Unique Situations

HCV Test and Cure

HCV Test and Cure Training Certificate

Screening and Diagnosis of Hepatitis C Infection

Evaluation, Staging, and Monitoring of Chronic Hepatitis C

Management of Cirrhosis-Related Complications

Evaluation and Preparation for Hepatitis C Treatment

Treatment of Hepatitis C Infection

Treatment of Key Populations and Unique Situations

Elbasvir-Grazoprevir

Glecaprevir-Pibrentasvir

Ledipasvir-Sofosbuvir

Ribavirin

Sofosbuvir

Sofosbuvir-Velpatasvir

Sofosbuvir-Velpatasvir-Voxilaprevir

Activity 5C. How to Use Liver Tox

Background

Activity Question

Which one of the following best describes St. John’s Wort in relation to potential hepatoxicity and drug interactions?

You must be signed in to customize your interaction with these questions.

HCV Test and Cure

Screening and Diagnosis of Hepatitis C Infection

Evaluation, Staging, and Monitoring of Chronic Hepatitis C

Management of Cirrhosis-Related Complications

Evaluation and Preparation for Hepatitis C Treatment

Treatment of Hepatitis C Infection

Treatment of Key Populations and Unique Situations

HCV Test and Cure

HCV Test and Cure Training Certificate

Screening and Diagnosis of Hepatitis C Infection

Evaluation, Staging, and Monitoring of Chronic Hepatitis C

Management of Cirrhosis-Related Complications

Evaluation and Preparation for Hepatitis C Treatment

Treatment of Hepatitis C Infection

Treatment of Key Populations and Unique Situations

Elbasvir-Grazoprevir

Glecaprevir-Pibrentasvir

Ledipasvir-Sofosbuvir

Ribavirin

Sofosbuvir

Sofosbuvir-Velpatasvir

Sofosbuvir-Velpatasvir-Voxilaprevir

Activity 5C. How to Use Liver Tox

Learning Objective Performance Indicators

Background

Activity Question

Which one of the following best describes St. John’s Wort in relation to potential hepatoxicity and drug interactions?

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You must be signed in to customize your interaction with these questions.