Activity 4G. Glecaprevir-Pibrentasvir Treatment with Compensated Cirrhosis

Learning Objective Performance Indicators

  • Provide a rationale for treating all people with HCV except persons with less than a 12-month life expectancy
  • Adhere to inclusion and exclusion criteria for who is eligible to receive simplified HCV treatment
  • Choose an appropriate recommended regimen for simplified HCV treatment
  • Conduct laboratory monitoring for persons receiving simplified HCV treatment, including assessment for sustained virologic response
  • Manage incomplete treatment adherence based on time into treatment and number of days of missed doses

Activity Question

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A 46-year-old woman is newly diagnosed with HCV. Initial evaluation reveals that she has compensated cirrhosis. She meets all criteria for the simplified treatment algorithm and she is not pregnant. The only medication that she takes is escitalopram. The decision is made to treat with glecaprevir-pibrentasvir.

Which one of the following should be recommended for the total duration of treatment with glecaprevir-pibrentasvir?  

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