Activity 5C. NIH Liver Tox PDF Share Learning Objective Performance Indicators Perform follow-up monitoring of persons after treatment for chronic HCV Obtain an HCV RNA assay as appropriate to screen for HCV reinfection after a person clears HCV Administer priority immunizations for people with chronic HCV Engage a person with chronic or cleared HCV in a discussion about measures that promote liver health Institute routine screening for hepatocellular carcinoma and varices for persons with cirrhosis Instructions: Read the case history, then use the LiverTox link and read the brief summary on St. John's Wort, with a particular focus on the liver toxicity section.BackgroundA 57-year-old woman presents to your clinic for a routine follow-up appointment. She has a history of anxiety, depression, and chronic hepatitis C virus (HCV). She recently started taking St. John’s Wort for her anxiety and depression and has been seeing a therapist. She is getting ready to start on treatment for HCV, and she asks you if St. John’s Wort is safe for her liver.Open NIH Liver Tox Activity QuestionYou should answer this question after completing the activity. You must answer all of the questions before checking your work. This activity has a Check on Learning question. - Show Question Which one of the following best describes St. John’s Wort in relation to potential hepatoxicity and drug interactions? There is no evidence that St. John's Wort caused hepatotoxicity or any clinically-relevant drug interactions There is a high rate of hepatotoxicity directly caused by St. John's Wort St. John's Wort has effects on P450 enzyme system and may cause significant drug interactions Share by e-mail From:Enter your e-mail address To: Enter the e-mail address of the recipient Your Message: Check-On-LearningQuestionsThe Check-on-Learning Questions are short and topic related. They are meant to help you stay on track throughout each lesson and check your understanding of key concepts.You must be signed in to customize your interaction with these questions.